New HPLC column Tosoh TSKgel Alpha-M 7.8 mm x 30 cm 13 um TSK gel 18344
TSKgel Alpha columns are composed of spherical, hydrophilic methacrylate beads. Unlike TSKgel PW-type columns, which are stable at most to a 50% organic mixed with water, TSKgel Alpha-type columns are stable in a wide variety of organic solvents at concentrations up to 100%. The main application area for TSKgel Alpha columns is the analysis of polymers that are soluble in polar organic solvents. Examples include cellulose derivatives, polyimide, and sodium dodecylsulfate (all in DMF with 10mmol/L DMF), cleansing gel in methanol, and degree of saponification of polyvinylalcohol in HFIP. The mixed-bed column, TSKgel Alpha-M, has an extended linear calibration range, and is suitable for samples with a broad MW distribution as well as samples with unknown molecular weight.
TSKgel Alpha-M columns are so-called mixed-bed columns with an extended linear calibration range. They are packed with rigid, porous, polymer beads which show minimal shrinkage or swelling in different solvent systems. They are best used for the separation of polymers that are soluble in polar organic solvents such as methanol, ethanol, DMF, THF, HFIP, DMSO, 2-propanol, and acetonitrile.